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S100B as potential dia...

S100B as potential diagnostic marker for SRC protocols Main Image

S100B as potential diagnostic marker for SRC protocols

Thu 13 Feb 2025

Researchers discuss S100B as a potential diagnostic marker for sport-related concussion (SRC) protocols.

Researchers discuss S100B as a potential diagnostic marker for sport-related concussion (SRC) protocols.

Researchers measured the concentration of serum S100B in male professional rugby players, finding that it increases significantly following concussion.

The researchers recruited 14 rugby players who sustained 24 concussions over three seasons. 13 samples of serum were collected. Serum S100B levels remained stable pre- and post season, across multiple seasons. Concussion resulted in a temporary increase in S100B concentration, returning to pre-season levels by post-season.

The researchers conclude that S100B could be a useful diagnostic marker for improving SRC management protocols.

Reference: Kelly, A.M., McHugh, C., Hale,J., Cunningham, J., Boyle, N., Joyce, O., O’Connell, B., Farrell, G., & Wilson, F. (2024). A cross-season analysis of S100B as a potential marker of concussion in professional rugby players. Brain Injury.

DOI: https://doi.org/10.1080/02699052.2024.2429700

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